What is it?
COMET stands for Cluster Of Motifs E-value Tool. It finds statistically significant clusters of motifs in a DNA sequence. The motifs are represented using 4 x L matrices, which record the frequencies of the nucleotides A, C, G, and T at each position in the motif. The Web version of Comet allows you to select motifs from a small library that we have constructed, or you can enter your own matrices, for example by copying and pasting them directly from the TRANSFAC database.